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TargetMajor prion protein
LigandBDBM114322
Substrate/Competitorn/a
Meas. Tech.TRFRET-based cell-based high throughput dose response assay to identify inhibitors of cell surface Prion Protein (PRPC)
IC50 1927±n/a nM
Citation PubChem, PC TRFRET-based cell-based high throughput dose response assay to identify inhibitors of cell surface Prion Protein (PRPC) PubChem Bioassay(2014)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Major prion protein
Name:Major prion protein
Synonyms:ALTPRP | ASCR | CD_antigen=CD230 | PRIO_HUMAN | PRIP | PRNP | PRP | PrP27-30 | PrP33-35C | Prion protein | major prion protein preproprotein
Type:PROTEIN
Mol. Mass.:27671.97
Organism:Homo sapiens (Human)
Description:ChEMBL_158887
Residue:253
Sequence:
MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP
HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA
VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV
NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
ILLISFLIFLIVG
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  Blast E-value cutoff:
BDBM114322
n/a
NameBDBM114322
Synonyms:3-(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)sulfanyloxolan-2-one | 3-[(2,5,6-trimethyl-4-thieno[2,3-d]pyrimidinyl)thio]-2-oxolanone | 3-[(2,5,6-trimethylthieno[2,3-d]pyrimidin-4-yl)thio]tetrahydrofuran-2-one | MLS000566711 | SMR000153614 | cid_4881170
TypeSmall organic molecule
Emp. Form.C13H14N2O2S2
Mol. Mass.294.392
SMILESCc1sc2nc(C)nc(SC3CCOC3=O)c2c1C
Structure
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