| Reaction Details |
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 | Report a problem with these data |
| Target | Major prion protein |
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| Ligand | BDBM114417 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TRFRET-based cell-based high throughput dose response assay to identify inhibitors of cell surface Prion Protein (PRPC) |
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| IC50 | 1245±n/a nM |
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| Citation |  PubChem, PC TRFRET-based cell-based high throughput dose response assay to identify inhibitors of cell surface Prion Protein (PRPC) PubChem Bioassay(2014)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Major prion protein |
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| Name: | Major prion protein |
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| Synonyms: | ALTPRP | ASCR | CD_antigen=CD230 | PRIO_HUMAN | PRIP | PRNP | PRP | PrP27-30 | PrP33-35C | Prion protein | major prion protein preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27671.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_158887 |
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| Residue: | 253 |
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| Sequence: | MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQP
HGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGA
VVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCV
NITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPV
ILLISFLIFLIVG
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| BDBM114417 |
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| n/a |
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| Name | BDBM114417 |
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| Synonyms: | 6-bromanyl-2-(5-ethylthiophen-2-yl)-3-methyl-quinoline-4-carboxylic acid | 6-bromo-2-(5-ethyl-2-thienyl)-3-methyl-cinchoninic acid | 6-bromo-2-(5-ethyl-2-thiophenyl)-3-methyl-4-quinolinecarboxylic acid | 6-bromo-2-(5-ethylthien-2-yl)-3-methylquinoline-4-carboxylic acid | 6-bromo-2-(5-ethylthiophen-2-yl)-3-methylquinoline-4-carboxylic acid | MLS001195884 | SMR000558711 | cid_995260 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14BrNO2S |
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| Mol. Mass. | 376.268 |
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| SMILES | CCc1ccc(s1)-c1nc2ccc(Br)cc2c(C(O)=O)c1C |
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| Structure | 
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