| Reaction Details |
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 | Report a problem with these data |
| Target | Methyl-CpG-binding domain protein 2 |
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| Ligand | BDBM40004 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TRFRET-based biochemical high throughput dose response assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide |
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| IC50 | 43812±n/a nM |
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| Citation |  PubChem, PC TRFRET-based biochemical high throughput dose response assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Methyl-CpG-binding domain protein 2 |
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| Name: | Methyl-CpG-binding domain protein 2 |
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| Synonyms: | MBD2 | MBD2_HUMAN | Methyl-CpG binding domain protein 2 | Methyl-CpG-binding domain protein 2 (MBD2) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43278.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21595776 |
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| Residue: | 411 |
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| Sequence: | MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG
RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG
APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF
SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLN
TTLPIRQTASIFKQPVTKVTNHPSNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTEQII
KTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCK
AFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEMDIEMDSGDEA
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| BDBM40004 |
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| n/a |
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| Name | BDBM40004 |
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| Synonyms: | (4-oxidanylidenepyrimido[2,1-b][1,3]benzothiazol-2-yl)methyl 2-(6,7-dihydro-5H-cyclopenta[f][1]benzofuran-3-yl)ethanoate | (4-oxopyrimido[2,1-b][1,3]benzothiazol-2-yl)methyl 2-(6,7-dihydro-5H-cyclopenta[f][1]benzofuran-3-yl)acetate | 2-(6,7-dihydro-5H-cyclopenta[f]benzofuran-3-yl)acetic acid (4-ketopyrimido[2,1-b][1,3]benzothiazol-2-yl)methyl ester | 2-(6,7-dihydro-5H-cyclopenta[f]benzofuran-3-yl)acetic acid (4-oxo-2-pyrimido[2,1-b][1,3]benzothiazolyl)methyl ester | MLS000056010 | SMR000068496 | cid_3000165 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H18N2O4S |
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| Mol. Mass. | 430.476 |
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| SMILES | O=C(Cc1coc2cc3CCCc3cc12)OCc1cc(=O)n2c(n1)sc1ccccc21 |
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| Structure | 
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