| Reaction Details |
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 | Report a problem with these data |
| Target | Fibrinogen beta chain [164-491] |
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| Ligand | BDBM32108 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer |
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| IC50 | 17891±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Fibrinogen beta chain [164-491] |
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| Name: | Fibrinogen beta chain [164-491] |
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| Synonyms: | Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37647.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_28373962 |
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| Residue: | 328 |
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| Sequence: | DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
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| BDBM32108 |
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| n/a |
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| Name | BDBM32108 |
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| Synonyms: | 6-keto-7,8,9,10-tetrahydrophenothiazine-3-carboxylic acid methyl ester | 6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxylic acid methyl ester | MLS000100349 | SMR000082651 | cid_1258835 | methyl 4-oxo-2,3,4,10-tetrahydro-1H-phenothiazine-7-carboxylate | methyl 6-oxidanylidene-7,8,9,10-tetrahydrophenothiazine-3-carboxylate | methyl 6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13NO3S |
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| Mol. Mass. | 275.323 |
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| SMILES | COC(=O)c1ccc2N=C3CCCC(=O)C3Sc2c1 |t:8| |
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| Structure | 
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