Reaction Details |
| Report a problem with these data |
Target | Fibrinogen beta chain [164-491] |
---|
Ligand | BDBM114655 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer |
---|
IC50 | 21023±n/a nM |
---|
Citation | PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Fibrinogen beta chain [164-491] |
---|
Name: | Fibrinogen beta chain [164-491] |
Synonyms: | Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 37647.12 |
Organism: | Homo sapiens (Human) |
Description: | gi_28373962 |
Residue: | 328 |
Sequence: | DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
|
|
|
BDBM114655 |
---|
n/a |
---|
Name | BDBM114655 |
Synonyms: | MLS000529672 | N-[(1,2-dimethyl-5-indolyl)methyl]-2-naphthalenesulfonamide | N-[(1,2-dimethylindol-5-yl)methyl]naphthalene-2-sulfonamide | SMR000127190 | cid_5046151 |
Type | Small organic molecule |
Emp. Form. | C21H20N2O2S |
Mol. Mass. | 364.461 |
SMILES | Cc1cc2cc(CNS(=O)(=O)c3ccc4ccccc4c3)ccc2n1C |
Structure |
|