Reaction Details |
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Target | Fibrinogen beta chain [164-491] |
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Ligand | BDBM114663 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer |
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IC50 | 11685±n/a nM |
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Citation | PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Fibrinogen beta chain [164-491] |
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Name: | Fibrinogen beta chain [164-491] |
Synonyms: | Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 37647.12 |
Organism: | Homo sapiens (Human) |
Description: | gi_28373962 |
Residue: | 328 |
Sequence: | DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
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BDBM114663 |
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n/a |
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Name | BDBM114663 |
Synonyms: | 3-(1-amino-9,10-dioxoanthracen-2-yl)sulfanylpropanoic acid | 3-[(1-amino-9,10-diketo-2-anthryl)thio]propionic acid | 3-[(1-amino-9,10-dioxo-2-anthracenyl)thio]propanoic acid | 3-[1-azanyl-9,10-bis(oxidanylidene)anthracen-2-yl]sulfanylpropanoic acid | MLS001164928 | SMR000540155 | cid_4356619 |
Type | Small organic molecule |
Emp. Form. | C17H13NO4S |
Mol. Mass. | 327.354 |
SMILES | Nc1c(SCCC(O)=O)ccc2C(=O)c3ccccc3C(=O)c12 |
Structure |
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