| Reaction Details |
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 | Report a problem with these data |
| Target | Fibrinogen beta chain [164-491] |
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| Ligand | BDBM114654 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer |
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| IC50 | 27761±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Fibrinogen beta chain [164-491] |
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| Name: | Fibrinogen beta chain [164-491] |
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| Synonyms: | Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37647.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_28373962 |
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| Residue: | 328 |
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| Sequence: | DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
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| BDBM114654 |
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| n/a |
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| Name | BDBM114654 |
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| Synonyms: | 4-[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-1-piperazinecarboxylic acid ethyl ester | 4-[[3-(p-tolyl)-1,2,4-oxadiazol-5-yl]methyl]piperazine-1-carboxylic acid ethyl ester | MLS000063762 | SMR000075555 | cid_752372 | ethyl 4-[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]piperazine-1-carboxylate | ethyl 4-{[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-1-piperazinecarboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C17H22N4O3 |
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| Mol. Mass. | 330.3816 |
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| SMILES | CCOC(=O)N1CCN(Cc2nc(no2)-c2ccc(C)cc2)CC1 |
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| Structure | 
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