| Reaction Details |
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 | Report a problem with these data |
| Target | Fibrinogen beta chain [164-491] |
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| Ligand | BDBM114656 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer |
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| IC50 | 83285±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Fibrinogen beta chain [164-491] |
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| Name: | Fibrinogen beta chain [164-491] |
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| Synonyms: | Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37647.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_28373962 |
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| Residue: | 328 |
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| Sequence: | DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
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| BDBM114656 |
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| n/a |
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| Name | BDBM114656 |
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| Synonyms: | (5E)-5-[1-(4-aminoanilino)butylidene]-2,2-dimethyl-4,6-dioxo-1-cyclohexanecarboxylic acid methyl ester | (5E)-5-[1-(4-aminoanilino)butylidene]-4,6-diketo-2,2-dimethyl-cyclohexanecarboxylic acid methyl ester | 5-[1-(4-Amino-phenylamino)-but-(Z)-ylidene]-2,2-dimethyl-4,6-dioxo-cyclohexanecarboxylic acid methyl ester | MLS000559552 | SMR000149668 | cid_5904397 | methyl (5E)-5-[1-(4-aminoanilino)butylidene]-2,2-dimethyl-4,6-dioxocyclohexane-1-carboxylate | methyl (5E)-5-[1-[(4-aminophenyl)amino]butylidene]-2,2-dimethyl-4,6-bis(oxidanylidene)cyclohexane-1-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C20H26N2O4 |
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| Mol. Mass. | 358.4314 |
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| SMILES | CCCC(Nc1ccc(N)cc1)=C1C(=O)CC(C)(C)C(C(=O)OC)C1=O |w:12.25| |
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| Structure | 
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