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TargetFibrinogen beta chain [164-491]
LigandBDBM25525
Substrate/Competitorn/a
Meas. Tech.Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer
IC50 83135±n/a nM
Citation PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Fibrinogen beta chain [164-491]
Name:Fibrinogen beta chain [164-491]
Synonyms:Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN
Type:Enzyme Catalytic Domain
Mol. Mass.:37647.12
Organism:Homo sapiens (Human)
Description:gi_28373962
Residue:328
Sequence:
DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM25525
n/a
NameBDBM25525
Synonyms:24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21),23-nonaen-24-ium | CHEMBL490129 | Pseudochelerythrine | Veadent | cid_5154 | sanguinarine | sangvinarin
TypeSmall organic molecule
Emp. Form.C20H14NO4
Mol. Mass.332.3289
SMILESC[n+]1cc2c3OCOc3ccc2c2ccc3cc4OCOc4cc3c12
Structure
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