| Reaction Details |
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 | Report a problem with these data |
| Target | PC4 and SFRS1-interacting protein |
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| Ligand | BDBM34840 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization |
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| IC50 | 563.94±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization PubChem Bioassay(2014)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| PC4 and SFRS1-interacting protein |
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| Name: | PC4 and SFRS1-interacting protein |
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| Synonyms: | DFS70 | LEDGF | LEDGF/p75 | PSIP1 | PSIP1_HUMAN | PSIP2 | lens epithelium-derived growth factor p75 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60120.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_6708281 |
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| Residue: | 530 |
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| Sequence: | MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFP
YSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKE
DTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKR
GRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKE
EDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRR
NMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIK
NSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLY
NKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNG
GSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN
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| BDBM34840 |
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| n/a |
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| Name | BDBM34840 |
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| Synonyms: | MLS000393172 | N'-[(E)-(2,3-dihydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]-1-ethyl-2-methyl-benzimidazole-5-carbohydrazide | N'-[(E)-(2,3-dihydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-1-ethyl-2-methyl-5-benzimidazolecarbohydrazide | N'-[(E)-(2,3-dihydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-1-ethyl-2-methylbenzimidazole-5-carbohydrazide | N'-[(E)-[2,3-bis(oxidanyl)-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene]methyl]-1-ethyl-2-methyl-benzimidazole-5-carbohydrazide | SMR000247984 | cid_6089713 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N4O4 |
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| Mol. Mass. | 354.3599 |
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| SMILES | CCn1c(C)nc2cc(ccc12)C(=O)NN=Cc1ccc(O)c(O)c1O |w:15.16| |
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| Structure | 
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