| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
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| Ligand | BDBM119070 |
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| Substrate/Competitor | n/a |
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| IC50 | 1.67e+4±n/a nM |
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| Citation |  Hrast, M; Sosic, I; Sink, R; Gobec, S Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F. Bioorg Chem55:2-15 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
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| Name: | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
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| Synonyms: | EPT | Enoylpyruvate transferase | MURA_PSEAE | MurA (P. aeruginosa) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | UDP-N-acetylglucosamine enolpyruvyl transferase | murA |
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| Type: | Protein |
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| Mol. Mass.: | 44640.67 |
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| Organism: | Pseudomonas aeruginosa (G-proteobacteria) |
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| Description: | P. aeruginosa MurA |
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| Residue: | 421 |
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| Sequence: | MDKLIITGGNRLDGEIRISGAKNSALPILAATLLADTPVTVCNLPHLHDITTMIELFGRM
GVQPIIDEKLNVEVDASSIKTLVAPYELVKTMRASILVLGPMLARFGEAEVALPGGCAIG
SRPVDLHIRGLEAMGAQIEVEGGYIKAKAPAGGLRGGHFFFDTVSVTGTENLMMAAALAN
GRTVLQNAAREPEVVDLANCLNAMGANVQGAGSDTIVIEGVKRLGGARYDVLPDRIETGT
YLVAAAATGGRVKLKDTDPTILEAVLQKLEEAGAHISTGSNWIELDMKGNRPKAVNVRTA
PYPAFPTDMQAQFISMNAVAEGTGAVIETVFENRFMHVYEMNRMGAQILVEGNTAIVTGV
PKLKGAPVMATDLRASASLVIAGLVAEGDTLIDRIYHIDRGYECIEEKLQLLGAKIRRVP
G
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| BDBM119070 |
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| n/a |
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| Name | BDBM119070 |
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| Synonyms: | Cnicin (compound 5) |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24O7 |
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| Mol. Mass. | 364.3897 |
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| SMILES | OC[C@@H](O)C(=C)C(=O)OC1C\C=C\CC\C(CO)=C\[C@H]2OC(=O)C(=C)[C@H]12 |r,t:11,17| |
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| Structure | 
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