| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-N-acetylenolpyruvoylglucosamine reductase |
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| Ligand | BDBM119078 |
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| Substrate/Competitor | n/a |
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| Kd | 1.4e+2±n/a nM |
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| Citation |  Hrast, M; Sosic, I; Sink, R; Gobec, S Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F. Bioorg Chem55:2-15 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| UDP-N-acetylenolpyruvoylglucosamine reductase |
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| Name: | UDP-N-acetylenolpyruvoylglucosamine reductase |
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| Synonyms: | MURB_STAAU | MurB (S. aureus) | UDP-N-acetylenolpyruvoylglucosamine reductase | murB |
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| Type: | Protein |
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| Mol. Mass.: | 33791.48 |
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| Organism: | Staphylococcus aureus (Firmicutes) |
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| Description: | S. aureus MurB |
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| Residue: | 307 |
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| Sequence: | MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNE
IPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALT
GLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQGSLIKLTTKELELDYRNSII
QKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLI
QDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRII
GEHPKES
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| BDBM119078 |
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| n/a |
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| Name | BDBM119078 |
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| Synonyms: | MurB inhibitor (compound 15) |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16F3N3O2S |
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| Mol. Mass. | 407.409 |
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| SMILES | CCOC(=O)C(=NNc1cccc(c1)C(F)(F)F)C1=Nc2ccccc2SC1 |w:6.6,t:19| |
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| Structure | 
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