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Target5-lipoxygenase/FLAP
LigandBDBM283245
Substrate/Competitorn/a
Meas. Tech.Binding Assay
Ki 0.000±n/a nM
Citation Bacani GMEccles WFitzgerald AEGoldberg SDHack MDHawryluk NAJones WMKeith JMKrawczuk PLebsack ADLee-Dutra ALiu JMcClure KJMeduna SPPippel DJRosen MDSales ZS FLAP modulators US Patent  US9884878 Publication Date 2/6/2018
More Info.:Get all data from this article,  Assay Method
 
5-lipoxygenase/FLAP
Name:5-lipoxygenase/FLAP
Synonyms:5-lipoxygenase activating protein | 5-lipoxygenase-activating protein (FLAP) | FLAP | MK-886-binding protein
Type:Enzyme
Mol. Mass.:18159.90
Organism:Homo sapiens (Human)
Description:P20292
Residue:161
Sequence:
MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
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  Blast E-value cutoff:
BDBM283245
n/a
NameBDBM283245
Synonyms:4'-(5-aminopyrazin-2-yl)-3'-fluoro-N-((1S,2S)- 1-hydroxy-1-phenylpropan-2-yl)-N-methyl- [1,1'-biphenyl]-2-sulfonamide | US9745328, Compound 118 | US9884878, Compound 118
TypeSmall organic molecule
Emp. Form.C26H25FN4O3S
Mol. Mass.492.565
SMILESC[C@@H]([C@@H](O)c1ccccc1)N(C)S(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1 |r|
Structure
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