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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | DNA primase | ||
| Ligand | BDBM50336799 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Quatitative Inhibition Analysis Assay | ||
| pH | 8.8±n/a | ||
| IC50 | 8.2e+3± 1.3e+3 nM | ||
| Comments | extracted | ||
| Citation |  Biswas, T; Green, KD; Garneau-Tsodikova, S; Tsodikov, OV Discovery of inhibitors of Bacillus anthracis primase DnaG. Biochemistry52:6905-10 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| DNA primase | |||
| Name: | DNA primase | ||
| Synonyms: | DNA primase (Ba DnaG) | ||
| Type: | Protein | ||
| Mol. Mass.: | 68258.37 | ||
| Organism: | Bacillus anthracis (Firmicutes) | ||
| Description: | A0A6L8PXB3 | ||
| Residue: | 598 | ||
| Sequence: |
| ||
| BDBM50336799 | |||
| n/a | |||
| Name | BDBM50336799 | ||
| Synonyms: | 5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino)]tris[1,3-benzenesulfonate analogue | 8,8'-(Carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bisnaphthalene-1,3,5-trisulphonic acid | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID | 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonyl-imino]]bis-1,3,5-naphthalenetrisulfonic acid(suramin) | 8-[(4-methyl-3-{[3-({[3-({2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)phenyl]carbamoyl}amino)benzene]amido}benzene)amido]naphthalene-1,3,5-trisulfonic acid | CHEMBL265502 | Germanin | Suramin hexasodium | US8835659, Suramin | Urea derivative | suramin | ||
| Type | Small organic molecule | ||
| Emp. Form. | C51H40N6O23S6 | ||
| Mol. Mass. | 1297.28 | ||
| SMILES | Cc1ccc(cc1NC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(c3cc(cc(c23)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)c1)C(=O)Nc1ccc(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O | ||
| Structure | 
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