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TargetEnoyl-acyl carrier reductase
LigandBDBM50174768
Substrate/Competitorn/a
Meas. Tech.TgENR Inhibition Assay
pH7.5±n/a
IC50 3±0.0 nM
Commentsextracted
Citation Afanador GAMuench SPMcPhillie MFomovska ASchön ASchön YCheng GStec JFreundlich JSShieh HMAnderson JWJacobus DPFidock DAKozikowski APFishwick CWRice DWFreire EMcLeod RPrigge ST Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay. Biochemistry 52:9155-66 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Enoyl-acyl carrier reductase
Name:Enoyl-acyl carrier reductase
Synonyms:Enoyl-acyl carrier reductase (ENR) | Enoyl-acyl carrier reductase, putative
Type:PROTEIN
Mol. Mass.:43663.67
Organism:Toxoplasma gondii
Description:ChEMBL_1290812
Residue:417
Sequence:
MVGFKLLTLGAFVAGELTLVGPAGTMAFTVPNATGAKPLVTSVSVRPSWSSARQNAFSSS
SSRSQSSVRPHSAFVTNRLETAGETGTQHRAADSAAGVGAAQSAFPIDLRGQTAFVAGVA
DSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLPDGSLIEFAGVYP
LDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVHSLANGPEVTKPL
LETSRKGYLAASSNSAYSFVSLLQHFGPIMNEGGSAVTLSYLAAERVVPGYGGGMSSAKA
ALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKSFIDYAIDYSYNNAPLR
RDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHAMGQAVDSRSMPPLQRATQEIN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50174768
n/a
NameBDBM50174768
Synonyms:5‐chloro‐2‐(2‐chloro‐4‐hydroxyphenoxy)phenol (5) | 5-chloro-2-(2-chloro-4-hydroxyphenoxy)phenol | CHEMBL200379
TypeSmall organic molecule
Emp. Form.C12H8Cl2O3
Mol. Mass.271.096
SMILESOc1ccc(Oc2ccc(Cl)cc2O)c(Cl)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: