| Reaction Details |
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 | Report a problem with these data |
| Target | Prokineticin receptor 2 |
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| Ligand | BDBM121261 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Calcium Mobilization Assay |
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| Temperature | 310.15±n/a K |
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| Ki | 1.24±n/a nM |
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| Comments | extracted |
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| Citation |  Zhou, Q; Li, J; Huang, Q Prokineticin receptor antagonists and uses thereof US Patent US8722896 Publication Date 5/13/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prokineticin receptor 2 |
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| Name: | Prokineticin receptor 2 |
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| Synonyms: | Prokineticin receptor 2 (PRK2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 44473.96 |
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| Organism: | Cricetulus griseus (Chinese hamster) |
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| Description: | G3H407 |
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| Residue: | 391 |
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| Sequence: | MPPAGINMASQNKNTSFAPDLNPSQDHISSLPFNFSYSDYDLPLDGDEDMTKTQTFFAAK
IVIGVALAGIMLVCGIGNFVFIAALARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDY
YVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFL
IALVWMVSILIAIPSAYFTTETILDIVKNQEKIFCGQIWPVDQQLYYKSYFLFVFGLEFV
GPVVAMTLCYARISQELWFKAVPGFQTEQIRKRLRCRRKTVLLLMGILTAYVLCWAPFYG
FTIVRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTICFVTVKNNTMKYFKKMLLLHWQ
PSRYGSKSSADLDLKTSGVPATEEVDCIRLK
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| BDBM121261 |
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| n/a |
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| Name | BDBM121261 |
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| Synonyms: | US8722896, (-)-(3R)-1-(N-methyl-indol-4- ylmethyl)-N-(9-chloro-3,4- dihydro-2H-1,5-benzodioxepin- 7-ylmethyl)-N- isobutylpiperidine-3- carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C30H38ClN3O3 |
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| Mol. Mass. | 524.094 |
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| SMILES | CC(C)CN(Cc1cc(Cl)c2OCCCOc2c1)C(=O)C1CCCN(Cc2cccc3n(C)ccc23)C1 |
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| Structure | 
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