| Reaction Details |
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 | Report a problem with these data |
| Target | Prokineticin receptor 1 |
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| Ligand | BDBM121324 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Calcium Mobilization Assay |
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| Temperature | 310.15±n/a K |
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| Ki | 1.15±n/a nM |
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| Comments | extracted |
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| Citation |  Zhou, Q; Li, J; Huang, Q Prokineticin receptor antagonists and uses thereof US Patent US8722896 Publication Date 5/13/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prokineticin receptor 1 |
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| Name: | Prokineticin receptor 1 |
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| Synonyms: | Prokineticin receptor 1 (PRK1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 44908.29 |
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| Organism: | Cricetulus griseus (Chinese hamster) |
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| Description: | G3HIE5 |
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| Residue: | 399 |
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| Sequence: | MPPPAWMEPTVGALGENTTDTSTSFLSLVNARGAQAASFPFTLSYGDYDTALGEEEDVTK
SWTFFAARIVIGMALVAIMLVCGVGNFIFITTLARYKKLRNLTNLLIANLAISDFLVAIV
CCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRM
KCQTAAGLIFLVWSVSILIAIPAAYFTTETVLVIVESQEKIFCGQIWPVDQQVYYRSYFL
LVFGLEFVGPVVAMTLCYARVSRELWFKAVPGFQTEQIRRRLRCRRRTVLGLVCVLSAYV
LCWAPFYGFTIVRDFFPSVFVKEKHYLTAFYVVECIAMSNSMINTLCFVSVRNNTSKYLK
RILRLQWRASPSGSKASADLDLRTTGMPATEEVDCIGLK
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| BDBM121324 |
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| n/a |
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| Name | BDBM121324 |
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| Synonyms: | US8722896, (-)-(2R)-2-Methyl-3-((3- hydroxy)benzylamino)-N-(9- chloro-3,3-difluoro-3,4-dihydro- 2H-1,5-benzodioxepin-7- ylmethyl)-N- isobutylpropanamide |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33ClN2O4 |
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| Mol. Mass. | 460.994 |
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| SMILES | CC(C)CN(Cc1cc(Cl)c2OCCCOc2c1)C(=O)[C@H](C)CNCc1cccc(O)c1 |r| |
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| Structure | 
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