| Reaction Details |
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 | Report a problem with these data |
| Target | Glucagon receptor |
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| Ligand | BDBM123647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| pH | 7.4±n/a |
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| Ki | 20.7±n/a nM |
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| Citation |  Chakravarty, D; Kreutter, K; Powell, M; Shook, B; Song, F; Xu, G; Yang, S; Zhang, R; Zhao, B Picolinamido-propanoic acid derivatives useful as glucagon receptor antagonists US Patent US8748624 Publication Date 6/10/2014 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Glucagon receptor |
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| Name: | Glucagon receptor |
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| Synonyms: | GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54026.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47871 |
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| Residue: | 477 |
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| Sequence: | MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
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| BDBM123647 |
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| n/a |
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| Name | BDBM123647 |
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| Synonyms: | US8748624, 170 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H22Cl2F3N3O3 |
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| Mol. Mass. | 588.404 |
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| SMILES | OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(Cl)ccc1CNc1ccc(c(Cl)c1)-c1cccc(c1)C(F)(F)F |
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| Structure | 
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