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TargetCore-binding factor subunit beta
LigandBDBM123656
Substrate/Competitorn/a
Meas. Tech.FRET Assay
IC50 5500±n/a nM
Citation Bushweller, JHGrembecka, JIllendula, ADixon, L Inhibitors of inv(16) leukemia US Patent US8748618 Publication Date 6/10/2014
More Info.:Get all data from this article,  Assay Method
 
Core-binding factor subunit beta
Name:Core-binding factor subunit beta
Synonyms:CBFB | Core-binding factor subunit beta (CBFB) | PEBB_HUMAN
Type:Enzyme
Mol. Mass.:21507.90
Organism:Homo sapiens (Human)
Description:Q13951
Residue:182
Sequence:
MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
RP
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  Blast E-value cutoff:
BDBM123656
n/a
NameBDBM123656
Synonyms:US10562890, Compound 4a | US8748618, AI-4-52
TypeSmall organic molecule
Emp. Form.C13H11N3O
Mol. Mass.225.2459
SMILESCOc1cccc2[nH]c(nc12)-c1ccccn1
Structure
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