| Reaction Details |
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 | Report a problem with these data |
| Target | Core-binding factor subunit beta |
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| Ligand | BDBM123659 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET Assay |
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| IC50 | 1400±n/a nM |
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| Citation |  Bushweller, JH; Grembecka, J; Illendula, A; Dixon, L Inhibitors of inv(16) leukemia US Patent US8748618 Publication Date 6/10/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Core-binding factor subunit beta |
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| Name: | Core-binding factor subunit beta |
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| Synonyms: | CBFB | Core-binding factor subunit beta (CBFB) | PEBB_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 21507.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13951 |
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| Residue: | 182 |
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| Sequence: | MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
RP
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|
|
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| BDBM123659 |
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| n/a |
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| Name | BDBM123659 |
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| Synonyms: | US8748618, AI-4-70 (or) LD-2-21 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H15N3O |
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| Mol. Mass. | 253.2991 |
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| SMILES | CC(C)Oc1ccc2nc([nH]c2c1)-c1ccccn1 |
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| Structure | 
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