| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Core-binding factor subunit beta |
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| Ligand | BDBM50180732 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET Assay |
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| IC50 | 2300±n/a nM |
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| Citation |  Bushweller, JH; Grembecka, J; Illendula, A; Dixon, L Inhibitors of inv(16) leukemia US Patent US8748618 Publication Date 6/10/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Core-binding factor subunit beta |
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| Name: | Core-binding factor subunit beta |
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| Synonyms: | CBFB | Core-binding factor subunit beta (CBFB) | PEBB_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 21507.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13951 |
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| Residue: | 182 |
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| Sequence: | MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
RP
|
|
|
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| BDBM50180732 |
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| n/a |
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| Name | BDBM50180732 |
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| Synonyms: | 5-Chloro-2-pyridin-2-yl-1H-benzoimidazole | 5-chloro-2-(pyridin-2-yl)-1H-benzo[d]imidazole | 5-chloro-2-pyridin-2-yl-1(3)H-benzoimidazole | CHEMBL166127 | US8748618, LD-2-79 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8ClN3 |
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| Mol. Mass. | 229.665 |
|---|
| SMILES | Clc1ccc2nc([nH]c2c1)-c1ccccn1 |
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| Structure | 
|
|---|
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