Reaction Details |
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Target | Core-binding factor subunit beta |
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Ligand | BDBM123673 |
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Substrate/Competitor | n/a |
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Meas. Tech. | FRET Assay |
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IC50 | 1100±n/a nM |
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Citation | Bushweller, JH; Grembecka, J; Illendula, A; Dixon, L Inhibitors of inv(16) leukemia US Patent US8748618 Publication Date 6/10/2014 |
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More Info.: | Get all data from this article, Assay Method |
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Core-binding factor subunit beta |
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Name: | Core-binding factor subunit beta |
Synonyms: | CBFB | Core-binding factor subunit beta (CBFB) | PEBB_HUMAN |
Type: | Enzyme |
Mol. Mass.: | 21507.90 |
Organism: | Homo sapiens (Human) |
Description: | Q13951 |
Residue: | 182 |
Sequence: | MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARFQNACRDGRSEIAFVAT
GTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMILNGVCVIWKGWIDLQRLD
GMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEVRVSQLLAVTGKKTT
RP
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BDBM123673 |
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n/a |
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Name | BDBM123673 |
Synonyms: | US8748618, LD-2-23 |
Type | Small organic molecule |
Emp. Form. | C13H8F3N3 |
Mol. Mass. | 263.2179 |
SMILES | FC(F)(F)c1ccc2nc([nH]c2c1)-c1ccccn1 |
Structure |
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