| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase D |
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| Ligand | BDBM3003 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PLD In Vitro Kinetic Assay |
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| Temperature | 310.15±0 K |
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| IC50 | 700±n/a nM |
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| Citation |  Kulkarni, A; Quang, P; Curry, V; Keyes, R; Zhou, W; Cho, H; Baffoe, J; Torok, B; Stieglitz, K 1,3-disubstituted-4-aminopyrazolo [3, 4-d] pyrimidines, a new class of potent inhibitors for phospholipase D. Chem Biol Drug Des84:270-81 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase D |
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| Name: | Phospholipase D |
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| Synonyms: | Phospholipase D (PLD_sp) |
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| Type: | Protein |
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| Mol. Mass.: | 54006.04 |
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| Organism: | Streptomyces sp. PMF |
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| Description: | P84147 |
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| Residue: | 506 |
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| Sequence: | ADSATPHLDAVEQTLRQVSPGLEGDVWERTSGNKLDGSAADPSDWLLQTPGCWGDDKCAD
RVGTKRLLAKMTENIGNATRTVDISTLAPFPNGAFQDAIVAGLKESAAKGNKLKVRILVG
AAPVYHMNVIPSKYRDELTAKLGKAAENITLNVASMTTSKTAFSWNHSKILVVDGQSALT
GGINSWKDDYLDTTHPVSDVDLALTGPAAGSAGRYLDTLWTWTCQNKSNIASVWFAASGN
AGCMPTMHKDTNPKASPATGNVPVIAVGGLGVGIKDVDPKSTFRPDLPTASDTKCVVGLH
DNTNADRDYDTVNPEESALRALVASAKGHIEISQQDLNATCPPLPRYDIRLYDALAAKMA
AGVKVRIVVSDPANRGAVGSGGYSQIKSLSEISDTLRNRLANITGGQQAAKTAMCSNLQL
ATFRSSPNGKWADGHPYAQHHKLVSVDSSTFYIGSKNLYPSWLQDFGYIVESPEAAKQLD
AKLLDPQWKYSQETATVDYARGICNA
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| BDBM3003 |
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| n/a |
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| Name | BDBM3003 |
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| Synonyms: | 1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (11) | CHEMBL122243 | pyrazolopyrimidine deriv. 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N5 |
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| Mol. Mass. | 287.3186 |
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| SMILES | Nc1ncnc2n(nc(-c3ccccc3)c12)-c1ccccc1 |
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| Structure | 
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