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TargetSerine/threonine-protein kinase ILK-1
LigandBDBM123997
Substrate/Competitorn/a
Meas. Tech.In Vitro Ezyme Assay
Temperature313.15±n/a K
IC50 200±n/a nM
Commentsextracted
Citation Zhang ZDaynard TSWang SDu XChopiuk GBYan JChen JSviridov SV Pyrazolylbenzothiazole derivatives and their use as therapeutic agents US Patent  US8754233 Publication Date 6/17/2014
More Info.:Get all data from this article,  Assay Method
 
Serine/threonine-protein kinase ILK-1
Name:Serine/threonine-protein kinase ILK-1
Synonyms:Integrin-linked protein kinase (ILK) | Serine/threonine-protein kinase ILK-1
Type:Protein
Mol. Mass.:51429.75
Organism:Homo sapiens (Human)
Description:Q13418
Residue:452
Sequence:
MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI
NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV
ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG
TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP
RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD
MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA
LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH
VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
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  Blast E-value cutoff:
BDBM123997
n/a
NameBDBM123997
Synonyms:US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-pyridin-4-yl-2H-pyrazol-3-ylamine
TypeSmall organic molecule
Emp. Form.C16H12FN5OS
Mol. Mass.341.363
SMILESCOc1cc2sc(nc2cc1F)-c1c(N)[nH]nc1-c1ccncc1
Structure
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