| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 2 |
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| Ligand | BDBM124258 |
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| Substrate/Competitor | n/a |
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| IC50 | 9.38e+3± 3.5e+2 nM |
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| Citation |  Yin, JP; Tang, CL; Gao, LX; Ma, WP; Li, JY; Li, Y; Li, J; Nan, FJ Design and synthesis of paracaseolide A analogues as selective protein tyrosine phosphatase 1B inhibitors. Org Biomol Chem12:3441-5 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Tyrosine-protein phosphatase non-receptor type 2 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 2 |
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| Synonyms: | PTN2_HUMAN | PTPN2 | PTPT | T-cell protein tyrosine phosphatase (TCPTP) | T-cell protein-tyrosine phosphatase | TC-PTP | TCPTP | Tyrosine-protein phosphatase non-receptor type 2 | Tyrosine-protein phosphatase non-receptor type 2 (TC-PTP) |
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| Type: | Protein |
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| Mol. Mass.: | 48481.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P17706 |
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| Residue: | 415 |
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| Sequence: | MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW
PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD
DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA
FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
TAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL
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| BDBM124258 |
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| n/a |
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| Name | BDBM124258 |
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| Synonyms: | (1S,4S,5R,10R,11S,12R)-5-dodecyl-1,10-dimethyl-3,8-dioxo-2,9,13-trioxatetracyclo[8.2.1.0⁴,.0⁷,]tridec-6-ene-4-carbaldehyde (14) |
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| Type | Small organic molecule |
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| Emp. Form. | C25H36O6 |
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| Mol. Mass. | 432.5497 |
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| SMILES | CCCCCCCCCCCC[C@@H]1C=C2[C@@H]3[C@H]4[C@](C)(OC(=O)[C@@]14C=O)O[C@]3(C)OC2=O |r,c:13| |
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| Structure | 
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