Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCalcitonin gene-related peptide (CGRP alpha)
LigandBDBM126180
Substrate/Competitorn/a
Meas. Tech.Binding Assay
pH7.4±n/a
Temperature298.15±n/a K
Ki 58±n/a nM
Commentsextracted
Citation Stump CAQuigley AG CGRP receptor antagonists US Patent  US8778957 Publication Date 7/15/2014
More Info.:Get all data from this article,  Assay Method
 
Calcitonin gene-related peptide (CGRP alpha)
Name:Calcitonin gene-related peptide (CGRP alpha)
Synonyms:CGRP | Calcitonin gene-related peptide 1
Type:Enzyme
Mol. Mass.:13902.80
Organism:Homo sapiens (Human)
Description:P06881
Residue:128
Sequence:
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQNYVQ
MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG
RRRRDLQA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM126180
n/a
NameBDBM126180
Synonyms:US8778957, 61
TypeSmall organic molecule
Emp. Form.C34H35N5O3
Mol. Mass.561.6734
SMILESCC(C)(C)OC(=O)N1CCN(Cc2ccc3cc4C[C@@]5(Cc4cc3n2)C(=O)Nc2ncccc52)CC1c1ccccc1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: