Reaction Details | |||
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Report a problem with these data | |||
Target | Cyclin-T1 | ||
Ligand | BDBM126551 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | IMAP Assay | ||
IC50 | 0.00036±n/a nM | ||
Citation | Barsanti, PA; Hu, C; Jin, J; Keyes, R; Kucejko, R; Lin, X; Pan, Y; Pfister, KB; Sendzik, M; Sutton, J; Wan, L Heteroaryl compounds and their uses US Patent US8778951 Publication Date 7/15/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
Cyclin-T1 | |||
Name: | Cyclin-T1 | ||
Synonyms: | CCNT1 | CCNT1_HUMAN | CycT | CycT1 | Cyclin T | Cyclin T1 | Cyclin-T | ||
Type: | Enzyme Subunit | ||
Mol. Mass.: | 80712.40 | ||
Organism: | Homo sapiens (Human) | ||
Description: | n/a | ||
Residue: | 726 | ||
Sequence: |
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BDBM126551 | |||
n/a | |||
Name | BDBM126551 | ||
Synonyms: | US8778951, 362 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H32ClF3N6O2 | ||
Mol. Mass. | 553.019 | ||
SMILES | FC(F)(F)OCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1 |r,wU:11.14,wD:8.7,(8.67,2.7,;7.34,1.93,;7.34,.39,;8.67,1.16,;6,2.7,;4.67,1.93,;3.33,2.7,;2,1.93,;.67,2.7,;.67,4.24,;-.67,5.01,;-2,4.24,;-2,2.7,;-.67,1.93,;-3.33,5.01,;-4.67,4.23,;-4.67,2.69,;-6,1.92,;-7.34,2.69,;-8.67,1.92,;-7.34,4.23,;-6,5,;-6,.38,;-7.34,-.39,;-7.34,-1.93,;-6,-2.7,;-4.67,-1.93,;-3.33,-2.7,;-2,-1.93,;-.67,-2.7,;-.67,-4.24,;.67,-5.01,;2,-4.24,;2,-2.7,;.67,-1.93,;-.67,-1.16,;-.67,.38,;-4.67,-.39,)| | ||
Structure |