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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | RAC-beta serine/threonine-protein kinase | ||
| Ligand | BDBM126560 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Inhibition Assay | ||
| pH | 7.5±n/a | ||
| IC50 | 0.71±n/a nM | ||
| Comments | extracted | ||
| Citation |  Nakamura, M; Niiyama, K; Kamijo, K; Ohkubo, M; Shimomura, T Imidazo-oxazine compound or salt thereof US Patent US8772283 Publication Date 7/8/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| RAC-beta serine/threonine-protein kinase | |||
| Name: | RAC-beta serine/threonine-protein kinase | ||
| Synonyms: | AKT2 | AKT2_HUMAN | PKB beta | Protein kinase Akt-2 | Protein kinase B (Akt 2) | Protein kinase B beta (AKT2) | Protein kinase B, beta | RAC-PK-beta | RAC-alpha serine/threonine-protein kinase (AKT2) | RAC-beta serine/threonine-protein kinase | RAC-beta serine/threonine-protein kinase (AKT2) | Serine/threonine-protein kinase AKT | Serine/threonine-protein kinase AKT2 | Serine/threonine-protein kinase Rac alpha/beta | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 55766.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 481 | ||
| Sequence: |
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| BDBM126560 | |||
| n/a | |||
| Name | BDBM126560 | ||
| Synonyms: | US8772283, 4 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H24FN3O2S | ||
| Mol. Mass. | 473.562 | ||
| SMILES | NC1(CC(O)(C1)C1CC1)c1ccc(cc1)-c1nc2-c3c(F)cccc3OCn2c1-c1ccsc1 |(7.56,3.47,;6.23,4.24,;5.14,5.33,;6.31,6.43,;6.36,7.97,;7.32,5.33,;4.9,7.07,;3.57,6.3,;4.13,8.4,;4.89,3.47,;3.56,4.24,;2.23,3.47,;2.23,1.93,;3.56,1.16,;4.89,1.93,;.93,1.09,;-.5,1.64,;-1.47,.45,;-3.01,.45,;-3.78,1.78,;-2.69,2.87,;-5.32,1.78,;-6.09,.45,;-5.32,-.89,;-3.78,-.89,;-3.01,-2.22,;-1.47,-2.22,;-.7,-.89,;.85,-.45,;2.06,-1.41,;3.49,-.85,;4.46,-2.05,;3.62,-3.34,;2.14,-2.94,)| | ||
| Structure | 
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