Reaction Details | |||
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Target | RAC-beta serine/threonine-protein kinase | ||
Ligand | BDBM126581 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Kinase Inhibition Assay | ||
pH | 7.5±n/a | ||
IC50 | 0.27±n/a nM | ||
Comments | extracted | ||
Citation | Nakamura, M; Niiyama, K; Kamijo, K; Ohkubo, M; Shimomura, T Imidazo-oxazine compound or salt thereof US Patent US8772283 Publication Date 7/8/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
RAC-beta serine/threonine-protein kinase | |||
Name: | RAC-beta serine/threonine-protein kinase | ||
Synonyms: | AKT2 | AKT2_HUMAN | PKB beta | Protein kinase Akt-2 | Protein kinase B (Akt 2) | Protein kinase B beta (AKT2) | Protein kinase B, beta | RAC-PK-beta | RAC-alpha serine/threonine-protein kinase (AKT2) | RAC-beta serine/threonine-protein kinase | RAC-beta serine/threonine-protein kinase (AKT2) | Serine/threonine-protein kinase AKT | Serine/threonine-protein kinase AKT2 | Serine/threonine-protein kinase Rac alpha/beta | ||
Type: | Enzyme | ||
Mol. Mass.: | 55766.64 | ||
Organism: | Homo sapiens (Human) | ||
Description: | n/a | ||
Residue: | 481 | ||
Sequence: |
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BDBM126581 | |||
n/a | |||
Name | BDBM126581 | ||
Synonyms: | US8772283, 25 | ||
Type | Small organic molecule | ||
Emp. Form. | C31H31N3O4 | ||
Mol. Mass. | 509.5955 | ||
SMILES | COc1cc(OC)c2-c3nc(c(-c4ccccc4)n3COc2c1)-c1ccc(cc1)C1(N)CC(O)(C1)C1CC1 |(-8.4,-.89,;-7.63,.45,;-6.09,.45,;-5.32,1.78,;-3.78,1.78,;-2.69,2.87,;-3.09,4.36,;-3.01,.45,;-1.47,.45,;-.5,1.64,;.93,1.09,;.85,-.45,;2.06,-1.41,;1.66,-2.89,;2.75,-3.98,;4.23,-3.58,;4.63,-2.1,;3.54,-1.01,;-.7,-.89,;-1.47,-2.22,;-3.01,-2.22,;-3.78,-.89,;-5.32,-.89,;2.23,1.93,;2.23,3.47,;3.56,4.24,;4.89,3.47,;4.89,1.93,;3.56,1.16,;6.23,4.24,;7.56,3.47,;5.14,5.33,;6.31,6.43,;6.36,7.97,;7.32,5.33,;4.9,7.07,;3.57,6.3,;4.13,8.4,)| | ||
Structure |