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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Gag-Pol polyprotein | ||
| Ligand | BDBM126676 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Alphascreen Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 277.15±n/a K | ||
| IC50 | 55.4±n/a nM | ||
| Citation |  Bardiot, D; Chaltin, P; Christ, F; Debyser, Z; De Maeyer, M; Marchand, A; Marchand, D; Voet, A Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors US Patent US8785638 Publication Date 7/22/2014 | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Gag-Pol polyprotein | |||
| Name: | Gag-Pol polyprotein | ||
| Synonyms: | Gag-Pol polyprotein | POL_HV1BR | Protease | gag-pol | ||
| Type: | Protein | ||
| Mol. Mass.: | 163312.58 | ||
| Organism: | Human immunodeficiency virus type 1 (HIV-1) | ||
| Description: | P03367 | ||
| Residue: | 1447 | ||
| Sequence: |
| ||
| BDBM126676 | |||
| n/a | |||
| Name | BDBM126676 | ||
| Synonyms: | US8785638, 161 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H30N2O3S | ||
| Mol. Mass. | 426.572 | ||
| SMILES | [NH4+].CCCC(C([O-])=O)c1c(C)nc2sc3CCCCc3c2c1-c1ccc(C)cc1O |(6.21,-1.54,;3.65,2.31,;3.65,.77,;2.32,,;2.32,-1.54,;3.65,-2.31,;4.98,-1.54,;3.65,-3.85,;.98,-2.31,;.98,-3.85,;2.32,-4.62,;-.35,-4.62,;-1.68,-3.85,;-3.15,-4.33,;-4.05,-3.08,;-5.59,-2.92,;-6.21,-1.51,;-5.31,-.27,;-3.77,-.43,;-3.15,-1.83,;-1.68,-2.31,;-.35,-1.54,;-.35,,;.98,.77,;.98,2.31,;-.35,3.08,;-.35,4.62,;-1.68,2.31,;-1.68,.77,;-3.02,,)| | ||
| Structure | 
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