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TargetBaculoviral IAP repeat-containing protein 3 [238-349]
LigandBDBM130048
Substrate/Competitorn/a
Meas. Tech.Fluorescence Polarization-Based Assays
IC50<20±n/a nM
Citation Wang, SSun, H Bivalent diazo bicyclic Smac mimetics and the uses thereof US Patent US8815927 Publication Date 8/26/2014
More Info.:Get all data from this article,  Assay Method
 
Baculoviral IAP repeat-containing protein 3 [238-349]
Name:Baculoviral IAP repeat-containing protein 3 [238-349]
Synonyms:API2 | Apoptosis inhibitor 2 | BIRC3 | BIRC3_HUMAN | Baculoviral IAP repeat-containing protein 3 | HIAP-1 | Inhibitor of apoptosis protein 1 | MIHC | RNF49 | TNFR2-TRAF-signaling complex protein 1 | cIAP-2 BIR3
Type:BIR3 domain
Mol. Mass.:12945.93
Organism:Homo sapiens (Human)
Description:Human cIAP2 BIR3 domain (residues 238-349) was used in binding assays.
Residue:112
Sequence:
QLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDG
GLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTS
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  Blast E-value cutoff:
BDBM130048
n/a
NameBDBM130048
Synonyms:US8815927, SM-1259
TypeSmall organic molecule
Emp. Form.C62H78N12O7
Mol. Mass.1103.3589
SMILESCN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)c1nc2c(cccc2[nH]1)-c1ccccc1)C(=O)CCCCOCCCCC(=O)N1CC[C@H]2CC[C@H](N2C(=O)[C@H](C1)NC(=O)[C@H](C)NC)c1nc2c(cccc2[nH]1)-c1ccccc1 |r|
Structure
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