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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM130069 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM130069 | |||
| n/a | |||
| Name | BDBM130069 | ||
| Synonyms: | US8815901, 22 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H22Cl2N6O3 | ||
| Mol. Mass. | 501.365 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ncc(CN(C)C)[nH]2)c2nccnc12 |(7.31,3.91,;8.08,2.57,;7.31,1.24,;8.08,-.1,;7.31,-1.43,;8.08,-2.76,;9.62,-2.76,;5.77,-1.43,;5,-2.76,;5,-.1,;5.77,1.24,;5,2.57,;3.46,-.1,;2.69,1.24,;1.15,1.24,;.38,-.1,;-1.16,-.1,;-1.93,1.24,;-1.93,-1.43,;-3.47,-1.43,;-4.37,-.18,;-5.84,-.66,;-5.84,-2.2,;-7.17,-2.97,;-8.51,-2.2,;-9.84,-2.97,;-8.51,-.66,;-4.37,-2.67,;1.15,-1.43,;.38,-2.76,;1.15,-4.1,;2.69,-4.1,;3.46,-2.76,;2.69,-1.43,)| | ||
| Structure | 
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