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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102541 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 32±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102541 | |||
| n/a | |||
| Name | BDBM102541 | ||
| Synonyms: | US8536175, 152 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H25ClFN5O5S | ||
| Mol. Mass. | 586.034 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1F)-c1ccc(C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cn2)c2nccnc12 |(8.08,4,;8.85,2.67,;8.08,1.33,;8.85,,;8.08,-1.33,;8.85,-2.67,;10.39,-2.67,;6.54,-1.33,;5.77,-2.67,;5.77,,;6.54,1.33,;5.77,2.67,;4.23,,;3.46,1.33,;1.92,1.33,;1.15,,;-.39,,;-1.15,1.33,;-1.15,-1.33,;-2.69,-1.33,;-3.46,,;-5,,;-5.77,-1.33,;-7.31,-1.33,;-8.08,,;-9.62,,;-10.39,1.33,;-9.62,2.67,;-10.39,4,;-8.85,4,;-8.08,2.67,;-7.31,1.33,;-5,-2.67,;-3.46,-2.67,;1.92,-1.33,;1.15,-2.67,;1.92,-4,;3.46,-4,;4.23,-2.67,;3.46,-1.33,)| | ||
| Structure | 
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