| Reaction Details |
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 | Report a problem with these data |
| Target | Protein UL24 homolog |
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| Ligand | BDBM130377 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Nuclear Magnetic Resonance (NMR) Assay |
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| pH | 8±n/a |
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| IC50 | 3.7e+3± 7e+2 nM |
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| Comments | extracted |
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| Citation |  Gable, JE; Lee, GM; Jaishankar, P; Hearn, BR; Waddling, CA; Renslo, AR; Craik, CS Broad-spectrum allosteric inhibition of herpesvirus proteases. Biochemistry53:4648-60 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein UL24 homolog |
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| Name: | Protein UL24 homolog |
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| Synonyms: | Kaposi's sarcoma-associated herpesvirus protease (KSHV Pr) | ORF20 | UL24_HHV8P |
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| Type: | Protein |
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| Mol. Mass.: | 28447.41 |
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| Organism: | Human herpesvirus 8 |
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| Description: | Q2HRB2 |
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| Residue: | 257 |
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| Sequence: | MVRPTEAEVKKSLSRLPAARKRAGNRAHLATYRRLLKYSTLPDLWRFLSSRPQNPPLGHH
RLFFEVTLGHRIADCVILVSGGHQPVCYVVELKTCLSHQLIPTNTVRTSQRAQGLCQLSD
SIHYIAHSAPPGTEAWTITPLLIFKNQKTLKTVYSESPGAFPTPVHTTEGKLCAFLTARE
NADIRKVLSKVPKKPKMDRGGKILGPTPGKRAVYSQAHHGRNKKGRPWTAQPTRAKSRTK
DKGTPAFPRAGPACSGP
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| BDBM130377 |
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| n/a |
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| Name | BDBM130377 |
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| Synonyms: | N-[2-Benzyl-4-(methylsulfonylcarbamoyl)phenyl]-6-(cyclohexylmethyl)pyridine-2- carboxamide (3) |
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| Type | Small organic molecule |
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| Emp. Form. | C28H31N3O4S |
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| Mol. Mass. | 505.628 |
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| SMILES | CS(=O)(=O)NC(=O)c1ccc(NC(=O)c2cccc(CC3CCCCC3)n2)c(Cc2ccccc2)c1 |
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| Structure | 
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