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TargetArginase (SmARG)
LigandBDBM130380
Substrate/Competitorn/a
Meas. Tech.ITC
pH8.5±0
Kd 3.6e+2± 8e+1 nM
Citation Hai YEdwards JEVan Zandt MCHoffmann KFChristianson DW Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis Biochemistry 53:4671-4684 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Arginase (SmARG)
Name:Arginase (SmARG)
Synonyms:n/a
Type:Protein
Mol. Mass.:39912.83
Organism:Schistosoma mansoni (flatworms)
Description:Q6WVP6
Residue:364
Sequence:
MLKSVATPYYPIQDEKPKLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDG
IQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKHTVELSGSK
STPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVK
ELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEA
VIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKL
SVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHM
QTKQ
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  Blast E-value cutoff:
BDBM130380
n/a
NameBDBM130380
Synonyms:nor-N-hydroxy-L-arginine (nor-NOHA)
TypeSmall organic molecule
Emp. Form.C6H14N3O3
Mol. Mass.176.1931
SMILESN\C(CCC[C@H]([NH3+])C([O-])=O)=[NH+]/O |r|
Structure
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