| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase |
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| Ligand | BDBM130381 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ITC |
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| pH | 8.5±0 |
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| Kd | 5.4e+2± 8e+1 nM |
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| Citation |  Hai, Y; Edwards, JE; Van Zandt, MC; Hoffmann, KF; Christianson, DW Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis Biochemistry53:4671-4684 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase |
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| Name: | Arginase |
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| Synonyms: | Arginase (SmARG) |
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| Type: | Protein |
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| Mol. Mass.: | 39912.83 |
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| Organism: | Schistosoma mansoni (flatworms) |
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| Description: | Q6WVP6 |
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| Residue: | 364 |
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| Sequence: | MLKSVATPYYPIQDEKPKLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDG
IQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKHTVELSGSK
STPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVK
ELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEA
VIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKL
SVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHM
QTKQ
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| BDBM130381 |
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| n/a |
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| Name | BDBM130381 |
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| Synonyms: | (R)-2-amino-6-borono-2-[1-(3,4-dichlorobenzyl)piperidin-4-yl]hexanoic acid (ABH-DP) |
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| Type | Small organic molecule |
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| Emp. Form. | C18H27BCl2N2O4 |
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| Mol. Mass. | 417.135 |
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| SMILES | N[C@](CCCCB(O)O)(C1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)C(O)=O |
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| Structure | 
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