| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphodiesterase 9A |
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| Ligand | BDBM131006 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Temperature | 303.15±n/a K |
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| IC50 | 10±n/a nM |
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| Comments | extracted |
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| Citation |  Okada M; Sato S; Kawade K; Gotanda K; Shinbo A; Nakano Y; Kobayashi H Substituted imidazo[1,5-A]quinoxalines as phosphodiesterase 9 inhibitors US Patent US8829000 Publication Date 9/9/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphodiesterase 9A |
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| Name: | 3',5'-cyclic phosphodiesterase |
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| Synonyms: | High affinity cGMP-specific 3'',5''-cyclic phosphodiesterase 9A | Phosphodiesterase 9A (PDE9) | Phosphodiesterase 9A (PDE9A) |
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| Type: | Protein |
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| Mol. Mass.: | 68488.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O76083 |
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| Residue: | 593 |
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| Sequence: | MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
VSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE
GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH
LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
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| BDBM131006 |
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| n/a |
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| Name | BDBM131006 |
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| Synonyms: | US8829000, 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12ClN3O |
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| Mol. Mass. | 261.707 |
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| SMILES | CC(C)c1ncc2n1c1ccc(Cl)cc1[nH]c2=O |
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| Structure | 
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