Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetC5a anaphylatoxin chemotactic receptor 1
LigandBDBM134586
Substrate/Competitorn/a
Meas. Tech.FLIPR Assay
IC50 1±n/a nM
Citation Adams, CMDarsigny, VFlyer, ANGelin, CFHurley, TBJi, NKarki, RGKawanami, TMeredith, ERao, CSerrano-Wu, MHSolovay, CF Tetrahydropyrido-pyridine and tetrahydropyrido-pyrimidine compounds and use thereof as C5a receptor modulators US Patent US8846656 Publication Date 9/30/2014
More Info.:Get all data from this article,  Assay Method
 
C5a anaphylatoxin chemotactic receptor 1
Name:C5a anaphylatoxin chemotactic receptor 1
Synonyms:C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88
Type:Enzyme
Mol. Mass.:39347.68
Organism:Homo sapiens (Human)
Description:P21730
Residue:350
Sequence:
MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM134586
n/a
NameBDBM134586
Synonyms:US8846656, 65-A
TypeSmall organic molecule
Emp. Form.C31H39N7
Mol. Mass.509.6883
SMILESCC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3CC(C3)N(C)C)c2C1)-c1c(C)ccc2[nH]nc(C)c12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: