| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Ligand | BDBM135460 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| pH | 8±n/a |
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| IC50 | 0.12±n/a nM |
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| Comments | extracted |
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| Citation |  Brown, MF; Marfat, A; Melnick, MJ; Reilly, U C-linked hydroxamic acid derivatives useful as antibacterial agents US Patent US8853258 Publication Date 10/7/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Name: | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Synonyms: | LPXC_PSEAE | Protein envA | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC) | UDP-3-O-acyl-GlcNAc deacetylase | UDP-3-O-acyl-GlcNAc deacetylase (LpxC) | envA | lpxC |
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| Type: | Enzyme |
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| Mol. Mass.: | 33428.15 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | P47205 |
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| Residue: | 303 |
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| Sequence: | MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFCRTDLDPVVEIPARAENVGET
TMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQ
EQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTS
FVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKIL
DAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRPA
AAV
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| BDBM135460 |
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| n/a |
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| Name | BDBM135460 |
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| Synonyms: | US8853258, 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N2O6S |
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| Mol. Mass. | 392.426 |
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| SMILES | CC(CCc1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O)(C(=O)NO)S(C)(=O)=O |
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| Structure | 
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