| Reaction Details |
|---|
 | Report a problem with these data |
| Target | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
|---|
| Ligand | BDBM135562 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Assay |
|---|
| pH | 8±n/a |
|---|
| IC50 | 0.0842±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Brown, MF; Marfat, A; Melnick, MJ; Reilly, U C-linked hydroxamic acid derivatives useful as antibacterial agents US Patent US8853258 Publication Date 10/7/2014 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| UDP-3-O-acyl-N-acetylglucosamine deacetylase |
|---|
| Name: | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
|---|
| Synonyms: | LPXC_PSEAE | Protein envA | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC) | UDP-3-O-acyl-GlcNAc deacetylase | UDP-3-O-acyl-GlcNAc deacetylase (LpxC) | envA | lpxC |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 33428.15 |
|---|
| Organism: | Pseudomonas aeruginosa |
|---|
| Description: | P47205 |
|---|
| Residue: | 303 |
|---|
| Sequence: | MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFCRTDLDPVVEIPARAENVGET
TMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQ
EQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTS
FVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKIL
DAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRPA
AAV
|
|
|
|---|
| BDBM135562 |
|---|
| n/a |
|---|
| Name | BDBM135562 |
|---|
| Synonyms: | US8853258, 215 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21NO6S |
|---|
| Mol. Mass. | 391.438 |
|---|
| SMILES | C[C@@](CCc1ccc(cc1)-c1ccc2OCOc2c1)(C(=O)NO)S(C)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
