Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 5A | ||
Ligand | BDBM135781 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Binding Inhibition Assay | ||
pH | 7.5±n/a | ||
Temperature | 298.15±n/a K | ||
Ki | 3.7±n/a nM | ||
Comments | extracted | ||
Citation | Kinoyama, I; Miyazaki, T; Koganemaru, Y; Washio, T; Hamaguchi, W Nitrogenous-ring acylguanidine derivative US Patent US8853242 Publication Date 10/7/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 5A | |||
Name: | 5-hydroxytryptamine receptor 5A | ||
Synonyms: | 5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A | ||
Type: | Enzyme | ||
Mol. Mass.: | 40266.25 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P47898 | ||
Residue: | 357 | ||
Sequence: |
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BDBM135781 | |||
n/a | |||
Name | BDBM135781 | ||
Synonyms: | US8853242, 114 | ||
Type | Small organic molecule | ||
Emp. Form. | C19H15F3N4O | ||
Mol. Mass. | 372.3438 | ||
SMILES | Cc1nc2ccc(cc2c(c1C)-c1c(F)cc(F)cc1F)C(=O)N=C(N)N |(-6,-4.62,;-4.67,-3.85,;-3.33,-4.62,;-2,-3.85,;-.67,-4.62,;.67,-3.85,;.67,-2.31,;-.67,-1.54,;-2,-2.31,;-3.33,-1.54,;-4.67,-2.31,;-6,-1.54,;-3.33,,;-4.67,.77,;-6,,;-4.67,2.31,;-3.33,3.08,;-3.33,4.62,;-2,2.31,;-2,.77,;-.67,,;2,-1.54,;2,,;3.33,-2.31,;4.67,-1.54,;6,-2.31,;4.67,,)| | ||
Structure |