| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM139222 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| Temperature | 298.15±n/a K |
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| Ki | 20000±n/a nM |
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| IC50 | 92000±n/a nM |
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| Comments | extracted |
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| Citation |  Wulff, JE; Brant, MG; Mason, JW; Bromba, CM; Boulanger, MJ Synthesis of bicyclic compounds and method for their use as therapeutic agents US Patent US8883846 Publication Date 11/11/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 51689.62 |
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| Organism: | Influenza A virus (A/Brisbane/59/2007(H1N1)) |
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| Description: | D5F1R0 |
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| Residue: | 470 |
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| Sequence: | MNPNQKIITIGSISIAIGIISLMLQIGNIISIWASHSIQTGSQNNTGICNQRIITYENST
WVNHTYVNINNTNVVAGEDKTSVTLAGNSSLCSISGWAIYTKDNSIRIGSKGDVFVIREP
FISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPLGEAPSPYNSKFESVAWS
ASACHDGMGWLTIGISGPDNGAVAVLKYNGIITGTIKSWKKQILRTQESECVCMNGSCFT
IMTDGPSNKAASYKIFKIEKGKVTKSIELNAPNFHYEECSCYPDTGIVMCVCRDNWHGSN
RPWVSFNQNLDYQIGYICSGVFGDNPRPEDGEGSCNPVTVDGANGVKGFSYKYDNGVWIG
RTKSNRLRKGFEMIWDPNGWTNTDSDFSVKQDVVAITDWSGYSGSFVQHPELTGLDCIRP
CFWVELVRGLPRENTTIWTSGSSISFCGVNSDTANWSWPDGAELPFTIDK
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|
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| BDBM139222 |
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| n/a |
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| Name | BDBM139222 |
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| Synonyms: | US8883846, 20 | US8883846, 31 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H16N2O5S |
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| Mol. Mass. | 276.309 |
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| SMILES | CC(=O)N[C@H]1CS(=O)(=O)[C@@H]2[C@H](C[C@@H](N)[C@H]12)C(O)=O |r| |
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| Structure | 
|
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