Reaction Details | |||
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Report a problem with these data | |||
Target | Phosphodiesterase | ||
Ligand | BDBM140184 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Assay | ||
pH | 6.5±n/a | ||
Temperature | 277.15±n/a K | ||
IC50 | 1300±n/a nM | ||
Comments | extracted | ||
Citation | Inoue, H; Murafuji, H; Hayashi, Y Thienopyrazole derivative having PDE7 inhibitory activity US Patent US8901315 Publication Date 12/2/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
Phosphodiesterase | |||
Name: | Phosphodiesterase | ||
Synonyms: | Phosphodiesterase 4 (PDE4) | ||
Type: | Protein | ||
Mol. Mass.: | 82059.36 | ||
Organism: | Mus musculus (Mouse) | ||
Description: | Q8VBU5 | ||
Residue: | 721 | ||
Sequence: |
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BDBM140184 | |||
n/a | |||
Name | BDBM140184 | ||
Synonyms: | US8901315, 416 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H35N5O2S | ||
Mol. Mass. | 457.632 | ||
SMILES | CN1CCN([C@H]2CC[C@@H](CC2)NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)C(=O)C1 |r,wU:8.11,wD:5.4,(9.6,2.19,;8.06,2.19,;7.29,.85,;5.75,.85,;4.98,2.19,;3.44,2.19,;2.67,3.52,;1.13,3.52,;.36,2.19,;1.13,.85,;2.67,.85,;-1.18,2.19,;-1.95,.85,;-1.18,-.48,;-3.49,.85,;-4.39,2.1,;-5.86,1.62,;-7.32,2.1,;-8.09,3.43,;-8.23,.85,;-7.32,-.39,;-7.72,-1.88,;-9.21,-2.28,;-9.6,-3.77,;-8.52,-4.85,;-7.03,-4.46,;-6.63,-2.97,;-5.86,.08,;-4.39,-.39,;5.75,3.52,;4.98,4.85,;7.29,3.52,)| | ||
Structure |