| Reaction Details |
|---|
 | Report a problem with these data |
| Target | EF-hand calcium-binding domain-containing protein 4B |
|---|
| Ligand | BDBM141402 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In-Vitro Inhibition Assay |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | 60.31±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Muthuppalaniappan, M; Viswanadha, S; Merikapudi, GS; Vakkalanka, SK Modulators of calcium release-activated calcium channel US Patent US8921364 Publication Date 12/30/2014 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| EF-hand calcium-binding domain-containing protein 4B |
|---|
| Name: | EF-hand calcium-binding domain-containing protein 4B |
|---|
| Synonyms: | CRACR2A | Calcium release-activated calcium (CRAC) | EFC4B_HUMAN | EFCAB4B | RAB46 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 45570.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9BSW2 |
|---|
| Residue: | 395 |
|---|
| Sequence: | MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ
TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ
NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK
QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM
EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE
TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR
EKAGLLKQLDFLRCVGGHWPVLRAPPRSLGSEGPV
|
|
|
|---|
| BDBM141402 |
|---|
| n/a |
|---|
| Name | BDBM141402 |
|---|
| Synonyms: | US10668051, Compound Example 28 | US8921364, 28 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H18FN5OS |
|---|
| Mol. Mass. | 383.443 |
|---|
| SMILES | Cc1nnsc1C(=O)Nc1ccc(c(F)c1)-n1nc(cc1C1CC1)C1CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
