| Reaction Details |
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 | Report a problem with these data |
| Target | Endothelial lipase |
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| Ligand | BDBM141542 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 14600±n/a nM |
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| Citation |  Zoller, G; Petry, S; Muller, G; Heuer, H; Tennagels, N Azole derivatives in the form of lipase and phospholipase inhibitors US Patent US8921404 Publication Date 12/30/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Endothelial lipase |
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| Name: | Endothelial lipase |
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| Synonyms: | Endothelial lipase (EL) | LIPE_RAT | Lipg |
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| Type: | Enzyme |
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| Mol. Mass.: | 55940.01 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q8VBX1 |
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| Residue: | 493 |
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| Sequence: | MRDPVFLLGFWSLYCCFPAGSLTTLRPQGSLRDEHHKPTGVPVTITTKPSVTFNIRTSKD
PEHEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQTREKEANV
VVVDWLPLAHQLYIDAVSNTRVVGRRVAGMLNWLQEKGEFSLGDVHLIGYSLGAHVAGYA
GNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGH
IDIYPNGGDFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCT
DPNRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPFRVYHYQLKVHMFSY
KNSGDIQPDLYITLYGSNADSQNLPLEIVEKIELNATNTFLVYTEEYLGDLFKIRLTWEG
VSSSWYNLWNEFRSYLSQPSSPSRELHIRRIRVKSGETQRKVAFCVQDPMKNSISPGQEL
WFYKCQNDCRVKN
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|
|
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| BDBM141542 |
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| n/a |
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| Name | BDBM141542 |
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| Synonyms: | US8921404, 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H19N3O2 |
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| Mol. Mass. | 261.3196 |
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| SMILES | CCCCCCNC(=O)Nc1noc2ccccc12 |
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| Structure | 
|
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