| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase II subunit alpha' |
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| Ligand | BDBM142774 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase Assay |
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| pH | 7.4±n/a |
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| Temperature | 303.15±n/a K |
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| IC50 | 0.09±n/a nM |
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| Comments | extracted |
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| Citation |  Purandare, AV; Fink, BE; Gavai, AV; Johnson, WL; Hart, AC; He, L; Huynh, TN; Inghrim, J; Mastalerz, H; Sang, X; Tarby, CM; Wan, H; Vaccaro, W; Zhang, G; Zhao, Y; Zimmermann, K Imidazotriazinecarbonitriles useful as kinase inhibitors US Patent US8940736 Publication Date 1/27/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase II subunit alpha' |
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| Name: | Casein kinase II subunit alpha' |
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| Synonyms: | CK2A2 | CSK22_HUMAN | CSNK2A2 | Casein kinase II alpha (prime) | Casein kinase II alpha' | Casein kinase II subunit alpha (CK2A2) | Casein kinase II subunit alpha (CSNK2A2) |
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| Type: | Protein |
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| Mol. Mass.: | 41223.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 350 |
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| Sequence: | MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
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| BDBM142774 |
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| n/a |
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| Name | BDBM142774 |
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| Synonyms: | US8940736, 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14N10 |
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| Mol. Mass. | 370.3708 |
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| SMILES | Cn1nc(C#N)c2cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)ccc12 |
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| Structure | 
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