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TargetGamma-aminobutyric acid receptor subunit alpha-2
LigandBDBM144250
Substrate/Competitorn/a
Meas. Tech.Radioligand Competition Binding Assay
Ki 21.7±n/a nM
Citation Omoto, KOwen, RMPryde, DCWatson, CATakeuchi, M Chemical compounds US Patent US8952008 Publication Date 2/10/2015
More Info.:Get all data from this article,  Assay Method
 
Gamma-aminobutyric acid receptor subunit alpha-2
Name:Gamma-aminobutyric acid receptor subunit alpha-2
Synonyms:GABA receptor alpha-2 subunit | GABRA2 | GBRA2_HUMAN | Gamma-aminobutyric acid receptor subunit alpha-2 (GABRA2)
Type:Protein
Mol. Mass.:51338.78
Organism:Homo sapiens (Human)
Description:P47869
Residue:451
Sequence:
MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
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  Blast E-value cutoff:
BDBM144250
n/a
NameBDBM144250
Synonyms:US8952008, 49
TypeSmall organic molecule
Emp. Form.C21H19FN4O2S
Mol. Mass.410.465
SMILESCCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)S(=O)(=O)CC
Structure
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