| Reaction Details |
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 | Report a problem with these data |
| Target | Lymphokine-activated killer T-cell-originated protein kinase |
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| Ligand | BDBM149044 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 0.97±n/a nM |
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| Comments | extracted |
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| Citation |  Nakamura, Y; Matsuo, Y; Hisada, S; Ahmed, F; Huntley, R; Sajjadi-Hashemi, Z; Jenkins, DM; Kargbo, RB; Cui, W; Gauuan, PJ; Walker, JR; Decornez, H; Gurram, M Tricyclic compounds and PBK inhibitors containing the same US Patent US8962648 Publication Date 2/24/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Lymphokine-activated killer T-cell-originated protein kinase |
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| Name: | Lymphokine-activated killer T-cell-originated protein kinase |
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| Synonyms: | 2.7.12.2 | CT84 | Cancer/testis antigen 84 | MAPKK-like protein kinase | Nori-3 | PBK | PDZ-binding kinase | SPK | Spermatogenesis-related protein kinase | T-LAK cell-originated protein kinase | TOPK | TOPK_HUMAN |
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| Type: | n/a |
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| Mol. Mass.: | 36072.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 322 |
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| Sequence: | MEGISNFKTPSKLSEKKKSVLCSTPTINIPASPFMQKLGFGTGVNVYLMKRSPRGLSHSP
WAVKKINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGE
KSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFE
TIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEM
MTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDESYQKVIELFSVC
TNEDPKDRPSAAHIVEALETDV
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| BDBM149044 |
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| n/a |
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| Name | BDBM149044 |
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| Synonyms: | US8962648, 278 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H19FN2O3S |
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| Mol. Mass. | 410.461 |
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| SMILES | OC1CCN(Cc2ccc(cc2F)-c2c(O)ccc3[nH]c(=O)c4sccc4c23)C1 |
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| Structure | 
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