| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 2 |
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| Ligand | BDBM150948 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Inhibition Assay |
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| Temperature | 310.15±n/a K |
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| IC50 | 14±n/a nM |
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| Comments | extracted |
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| Citation |  Maeda, DY; Zebala, JA Pyrimidinecarboxamides as CXCR2 modulators US Patent US8981106 Publication Date 3/17/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| C-X-C chemokine receptor type 2 |
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| Name: | C-X-C chemokine receptor type 2 |
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| Synonyms: | C-X-C chemokine receptor type 2 (CXCR-2) | C-X-C chemokine receptor type 2 (CXCR2) | CD_antigen=CD182 | CDw128b | CXCR-2 | CXCR2 | CXCR2_HUMAN | Chemokine receptor type 2 (CXCR2) | GRO/MGSA receptor | High affinity interleukin-8 receptor B | IL-8 receptor type 2 | IL-8R B | IL8RB | Interleukin-8 receptor B |
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| Type: | Protein |
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| Mol. Mass.: | 40767.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25025 |
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| Residue: | 360 |
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| Sequence: | MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFL
LSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCK
VVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPV
LLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFK
AHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATE
ILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
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|
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| BDBM150948 |
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| n/a |
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| Name | BDBM150948 |
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| Synonyms: | US8981106, 137 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H14FN3O5S |
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| Mol. Mass. | 415.395 |
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| SMILES | COC(=O)c1cc(on1)C(=O)CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1 |
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| Structure | 
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