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TargetMenin
LigandBDBM152232
Substrate/Competitorn/a
Meas. Tech.NMR Spectroscopy Assay
IC50 650±n/a nM
Citation Grembecka JCierpicki THess J Compositions and methods for treatment of leukemia US Patent  US8993552 Publication Date 3/31/2015
More Info.:Get all data from this article,  Assay Method
 
Menin
Name:Menin
Synonyms:MEN1 | SCG2
Type:Protein
Mol. Mass.:68022.55
Organism:Homo sapiens (Human)
Description:O00255
Residue:615
Sequence:
MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPE
LTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKK
VSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPVGTKLDSSGVAFAVVGACQALGLRDVHL
ALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKME
VAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGR
PDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCR
EDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQSQGTQSQGSALQDPECFAHLLR
FYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREAEAAEAEEPWGEEA
REGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVAGTARGPEGGSTA
QVPAPTASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTP
SDYTLSFLKRQRKGL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM152232
n/a
NameBDBM152232
Synonyms:US8993552, 67
TypeSmall organic molecule
Emp. Form.C18H25N5S2
Mol. Mass.375.555
SMILESCC(C)c1cc2c(ncnc2s1)N1CCN(CC1)C1=NCC(C)(C)S1 |t:21|
Structure
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